- Single dose vaccine valid for 10 years
- Valid for life after second dose
- Single dose vaccination provides cover for a period of 3 to 5 years.
Hep A and B
- Travellers to areas affected by meningococcal outbreaks should be vaccinated as well as travellers to Saudi Arabia for the Hajj and Umrah. Also recommended for university and hostel accommodation residents.
- Vaccines are available against serogroups A, C, W 135 and Y (quadrivalent)
- Single dose provides 5 year protection, boosting recommended
Paediatric Hep A
- Avaxim Junior
- Due to lack of availability of the adult dosage the paediatric vaccine can be used (two paediatric doses = one adult dose)
- Generally, one single vaccine provides protection within 2 to 4 weeks which lasts for approximately 6 months to 1 year. A single booster dose will maintain the protection for at least a further 10 years.
- Engerix B
- An initial vaccine with two booster doses administered over a six month period is required for full immunity.
- Pre-exposure vaccination which consists of two doses given 7 days apart will protect an individual who comes into contact with a potentially rabid animal and will allow for enough time to get post exposure prophylaxis without the need for rabies immunoglobin which is not readily available.
- The same vaccine is used if one is exposed to a potentially rabid animal.
- This vaccine is indicated for an individual who comes into contact with a potentially rabid animal with a category 3 exposure. RIG is derived from immunised human donors and is in short supply.
- Available as a single preparation or as part of the 4 in 1 Adacel Quadra
- One dose provides protection for 10 years, however a booster is recommended if an exposure occurs 5 or more years after the initial dose.
- Prevenar (PCV13)
- Indicated for individuals with splenic dysfunction, sickle cell disease, immune compromise, chronic lung, heart or liver disease, alcoholism, age over 65 and all smokers regardless of age
- Recommended as a booster one year after receiving Prevenar; should give lifelong protection but a booster can be administered for high-risk individuals after 5 years
- Part of the childhood vaccine programme; however, a booster is indicated at age 12 and for university and hostel accommodation residents as well as women who are planning to fall pregnant.
- Vaxigrip Tetra
- Recommended to all individuals over 6 months of age on a yearly basis. Released yearly based on the strains circulating in the population at the time and what is predicted to affect each hemisphere in the forthcoming winter.
- Recommended for children and university hostel residents or anyone staying in shared accommodation
- Zostervax (live vaccine)
- Recommended for people who have had chicken pox to prevent the development of shingles
- Risk for developing shingles increases with age, chronic conditions and immune compromise
- Shingrix (killed vaccine) – Section 21/off label use in South Africa
- Recombinant shingles vaccine is recommended for adults 50 years and older and adults with immune compromise
- The Shingrix vaccine is a 2-dose regimen
- The advantage of the recombinant vaccine is that it is not a live vaccine and can therefore be given to organ transplant recipients and severely immune compromised patients who cannot received a live vaccine
- Zostervax (live vaccine)
HPV (human papilloma virus)
- Protects against human papilloma virus types 6,11, 16 and 18 (quadrivalent) which cause cervical cancer
- Recommended to girls over the age of 9; given in 3 doses within a 6-month period
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